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If not neutralized by antioxidants, ROS may damage mitochondria over time, causing them to function less efficiently and to generate more damaging ROS in a self-perpetuating cycle

Our study demonstrated that naltrexone significantly attenuated the acute increase in Glx/tNAA during ketamine infusion compared to placebo, implying a potential interaction between opioidergic and glutamatergic systems, which may be of importance in understanding ketamines neurobiological effects

PubMed: 33146843Human observational ref-10.Sadowski M, Zawieja E, Chmurzynska A The impact of N-acetylcysteine on lactate, biomarkers of oxidative stress, immune response, and muscle damage: A systematic review and meta-analysis

As we age, the rate at which our bodies produce collagen decreases